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Describe how a peptide bond is formed between two amino acids to form a dipeptide. __

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Describe how a peptide bond is formed between two amino acids to form a
dipeptide.
__

Describe how a peptide bond is formed between two amino acids to form a dipeptide. __

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SaliMaster · Tutor for 5 years

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Peptide bond, a bond covalently linked, forms between two amino acids via a dehydration synthesis or condensation reaction, resulting in the loss of a water molecule. A peptide link CO-NH-, links two amino acid molecules in a dipeptide. Described in chemical reaction:<br /><br />**\(H_{2}N-CHR-COOH + H_{2}N-CHR'-COOH → H_{2}N-CHR-CO-NH-CHR'-COOH + H_{2}O\)**

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## Step 1: <br />A peptide bond forms between two amino acids during a process known as dehydration synthesis, or a condensation reaction. <br /><br />## Step 2: <br />In this process, the carboxyl group (-COOH) of one amino acid and the amino group (-NH2) of the other amino acid come close together. <br /><br />## Step 3:<br />The hydrogen atom from the amino group of one amino acid combines with the hydroxyl group (OH) from the carboxyl group of a second amino acid, creating a molecule of water (H2O). Thus, the term "dehydration synthesis."<br /><br />## Step 4:<br />The residue after the response is a peptide bond (-CO-NH-), joining the two amino acids together. <br /><br />## Step 5:<br />As specifically, when two amino acids link to form a dipeptide, this reaction results in the creation of one water molecule and a dipeptide essentially a molecule of two connected amino acids.<br /><br />### Formula of Peptide Bond Formation:<br />**\(H_{2}N-CHR-COOH + H_{2}N-CHR'-COOH \rightarrow H_{2}N-CHR-CO-NH-CHR'-COOH + H_{2}O\)**<br /><br />Where **R** and **R'** represent the side chains of the individual amino acids, which can vary.
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